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ITT1555

ITT1555
ITT1555
ITT1555
  • Gene/Protein: EXOG
  • Product Description: Immunotag™ Endo G-L1 Polyclonal Antibody
280.0000
Price in reward points: 294

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Immunotag™ Endo G-L1 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein Endo G-L1
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen The antiserum was produced against synthesized peptide derived from human ENDOGL1. AA range:171-220
Specificity Endo G-L1 Polyclonal Antibody detects endogenous levels of Endo G-L1 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name EXOG
Accession No. Q9Y2C4 Q8C163
Alternate Names EXOG; ENDOGL1; ENDOGL2; ENGL; Nuclease EXOG; mitochondrial; Endonuclease G-like 1; Endo G-like 1
Description exo/endonuclease G(EXOG) Homo sapiens This gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18. [provided by RefSeq, Feb 2009],
Cell Pathway/ Category Apoptosis_Inhibition,Apoptosis_Mitochondrial,Apoptosis_Overview,
Protein Expression Spleen,Subthalamic nucleus,
Subcellular Localization mitochondrial inner membrane,integral component of membrane,protein complex,
Protein Function cofactor:Divalent metal cations.,function:Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single stranded DNA and 5'-3' exonuclease activity.,miscellaneous:The active site contains 1 hydrated divalent metal cation that has only 1 direct interaction with the protein; all other interactions are via water molecules.,similarity:Belongs to the DNA/RNA non-specific endonuclease family.,subunit:Homodimer.,tissue specificity:Ubiquitous.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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