ITT1555
ITT1555
- Catalog: ITT1555
- Gene/Protein: EXOG
- Product Description: Immunotag™ Endo G-L1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Endo G-L1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ENDOGL1. AA range:171-220 |
| Specificity | Endo G-L1 Polyclonal Antibody detects endogenous levels of Endo G-L1 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | EXOG |
| Accession No. | Q9Y2C4 Q8C163 |
| Alternate Names | EXOG; ENDOGL1; ENDOGL2; ENGL; Nuclease EXOG; mitochondrial; Endonuclease G-like 1; Endo G-like 1 |
| Description | exo/endonuclease G(EXOG) Homo sapiens This gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18. [provided by RefSeq, Feb 2009], |
| Cell Pathway/ Category | Apoptosis_Inhibition,Apoptosis_Mitochondrial,Apoptosis_Overview, |
| Protein Expression | Spleen,Subthalamic nucleus, |
| Subcellular Localization | mitochondrial inner membrane,integral component of membrane,protein complex, |
| Protein Function | cofactor:Divalent metal cations.,function:Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single stranded DNA and 5'-3' exonuclease activity.,miscellaneous:The active site contains 1 hydrated divalent metal cation that has only 1 direct interaction with the protein; all other interactions are via water molecules.,similarity:Belongs to the DNA/RNA non-specific endonuclease family.,subunit:Homodimer.,tissue specificity:Ubiquitous., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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