ITT1598
ITT1598
- Catalog: ITT1598
- Gene/Protein: EPS8L1
- Product Description: Immunotag™ Eps8L1 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | EPS8L1 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,IF,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human ES8L1. AA range:411-460 |
Specificity | Eps8L1 Polyclonal Antibody detects endogenous levels of Eps8L1 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | EPS8L1 |
Accession No. | Q8TE68 Q8R5F8 |
Alternate Names | EPS8L1; DRC3; EPS8R1; PP10566; Epidermal growth factor receptor kinase substrate 8-like protein 1; EPS8-like protein 1; Epidermal growth factor receptor pathway substrate 8-related protein 1; EPS8-related protein 1 |
Description | EPS8 like 1(EPS8L1) Homo sapiens This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. At least two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
Protein Expression | Muscle,Placenta,Skin, |
Subcellular Localization | cytoplasm,cell-cell adherens junction,ruffle membrane,protein complex,extracellular exosome, |
Protein Function | function:Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton.,similarity:Belongs to the EPS8 family.,similarity:Contains 1 SH3 domain.,subunit:Interacts with ABI1. Part of a complex that contains SOS1, ABI1 and EPS8L2. Associates with F-actin.,tissue specificity:Detected in placenta., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |