ITT1603
ITT1603
- Catalog: ITT1603
- Gene/Protein: EPN3
- Product Description: Immunotag™ Epsin 3 Polyclonal Antibody
385.0000
Price in reward points: 385
Your shopping cart is empty!
Antibody Specification | |
Datasheet | |
Target Protein | EPSin 3 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human EPN3. AA range:401-450 |
Specificity | Epsin 3 Polyclonal Antibody detects endogenous levels of Epsin 3 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | EPN3 |
Accession No. | Q9H201 Q91W69 |
Alternate Names | EPN3; Epsin-3; EPS-15-interacting protein 3 |
Description | induction:In keratinocytes, by wounding or contact with collagen.,similarity:Belongs to the epsin family.,similarity:Contains 1 ENTH (epsin N-terminal homology) domain.,similarity:Contains 2 UIM (ubiquitin-interacting motif) repeats.,subcellular location:Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus.,tissue specificity:Detected in migrating keratinocytes from wounded skin, but not in differentiating keratinocytes or in normal skin. Detected in chronic wounds, basal cell carcinoma and ulcerative colitis., |
Cell Pathway/ Category | Endocytosis, |
Protein Expression | Colon,Placenta,Skin, |
Subcellular Localization | nucleus,nucleoplasm,clathrin-coated pit,extrinsic component of plasma membrane,clathrin-coated vesicle,intracellular membrane-bounded organelle,perinuclear region of cytoplasm,extracellular exosome, |
Protein Function | induction:In keratinocytes, by wounding or contact with collagen.,similarity:Belongs to the epsin family.,similarity:Contains 1 ENTH (epsin N-terminal homology) domain.,similarity:Contains 2 UIM (ubiquitin-interacting motif) repeats.,subcellular location:Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus.,tissue specificity:Detected in migrating keratinocytes from wounded skin, but not in differentiating keratinocytes or in normal skin. Detected in chronic wounds, basal cell carcinoma and ulcerative colitis., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |