ITT1695
ITT1695
- Catalog: ITT1695
- Gene/Protein: FGF1
- Product Description: Immunotag™ FGF-1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | FGF-1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from the Internal region of human FGF-1 |
| Specificity | FGF-1 Polyclonal Antibody detects endogenous levels of FGF-1 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | FGF1 |
| Accession No. | P05230 P61148 P61149 |
| Alternate Names | FGF1; FGFA; Fibroblast growth factor 1; FGF-1; Acidic fibroblast growth factor; aFGF; Endothelial cell growth factor; ECGF; Heparin-binding growth factor 1; HBGF-1 |
| Description | fibroblast growth factor 1(FGF1) Homo sapiens The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Jan 2009], |
| Cell Pathway/ Category | MAPK_ERK_Growth,MAPK_G_Protein,Regulates Actin and Cytoskeleton,Pathways in cancer,Melanoma, |
| Protein Expression | Brain stem,Glioma,Liver, |
| Subcellular Localization | extracellular region,proteinaceous extracellular matrix,extracellular space,nucleoplasm,nucleolus,cytosol,cell cortex, |
| Protein Function | function:The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors.,miscellaneous:This protein binds heparin, although less strongly than does bFGF.,similarity:Belongs to the heparin-binding growth factors family.,subunit:Monomer. Binds FGFR2. Forms a ternary complex containing 2 molecules each of FGFR2 and FGF1 for 1 heparin molecule. Found in a complex with FGFBP1, FGF1 and FGF2. Interacts with FGFBP1., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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