ITT1697
ITT1697
- Catalog: ITT1697
- Gene/Protein: FGF18
- Product Description: Immunotag™ FGF-18 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | FGF-18 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | IHC-p,IF,ELISA |
Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human FGF18. AA range:151-200 |
Specificity | FGF-18 Polyclonal Antibody detects endogenous levels of FGF-18 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | FGF18 |
Accession No. | O76093 O89101 |
Alternate Names | FGF18; Fibroblast growth factor 18; FGF-18; zFGF5 |
Description | fibroblast growth factor 18(FGF18) Homo sapiens The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | MAPK_ERK_Growth,MAPK_G_Protein,Regulates Actin and Cytoskeleton,Pathways in cancer,Melanoma, |
Protein Expression | Lung,Ovary, |
Subcellular Localization | extracellular region,extracellular space,nucleolus, |
Protein Function | function:Stimulates hepatic and intestinal proliferation.,similarity:Belongs to the heparin-binding growth factors family., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |