ITT1702
ITT1702
- Catalog: ITT1702
- Gene/Protein: FGFRL1
- Product Description: Immunotag™ FGFR-5 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | FGFR-5 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from FGFR-5 . at AA range: 130-210 |
| Specificity | FGFR-5 Polyclonal Antibody detects endogenous levels of FGFR-5 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | FGFRL1 |
| Accession No. | Q8N441 Q91V87 |
| Alternate Names | FGFRL1; FGFR5; FHFR; Fibroblast growth factor receptor-like 1; FGF receptor-like protein 1; FGF homologous factor receptor; FGFR-like protein; Fibroblast growth factor receptor 5; FGFR-5 |
| Description | fibroblast growth factor receptor-like 1(FGFRL1) Homo sapiens The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other |
| Protein Expression | Brain,Cartilage,Kidney,Pancreas, |
| Subcellular Localization | Golgi apparatus,plasma membrane,integral component of membrane,transport vesicle,cell-cell contact zone, |
| Protein Function | function:Has a negative effect on cell proliferation.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,subcellular location:Predominantly localized in the plasma membrane but also detected in the Golgi and in secretory vesicles.,subunit:Interacts with FGF2 with a low affinity.,tissue specificity:Expressed preferentially in cartilaginous tissues and pancreas. Highly expressed in the liver, kidney, heart, brain and skeletal muscle. Weakly expressed in the lung, small intestine and spleen., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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