ITT1707
ITT1707
- Catalog: ITT1707
- Gene/Protein: FBLN2
- Product Description: Immunotag™ Fibulin-2 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | Fibulin-2 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,IF,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human FBLN2. AA range:241-290 |
Specificity | Fibulin-2 Polyclonal Antibody detects endogenous levels of Fibulin-2 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | FBLN2 |
Accession No. | P98095 P37889 |
Alternate Names | FBLN2; Fibulin-2; FIBL-2 |
Description | fibulin 2(FBLN2) Homo sapiens This gene encodes an extracellular matrix protein, which belongs to the fibulin family. This protein binds various extracellular ligands and calcium. It may play a role during organ development, in particular, during the differentiation of heart, skeletal and neuronal structures. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008], |
Protein Expression | Fibroblast,Liver,Testis,Uterus, |
Subcellular Localization | extracellular region,proteinaceous extracellular matrix,extracellular matrix,extracellular exosome,extracellular vesicle, |
Protein Function | developmental stage:Widely expressed during embryonic development. Primarily detected within the neuropithelium, spinal ganglia and peripheral nerves.,function:Its binding to fibronectin and some other ligands is calcium dependent.,similarity:Belongs to the fibulin family.,similarity:Contains 11 EGF-like domains.,similarity:Contains 3 anaphylatoxin-like domains.,subunit:Homotrimer; disulfide-linked. Interacts with LAMA2.,tissue specificity:Component of both basement membranes and other connective tissues. Expressed in heart, placenta and ovary., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |