ITT1735
ITT1735
- Catalog: ITT1735
- Gene/Protein: FST
- Product Description: Immunotag™ Follistatin Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | FolliSTATin |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from Follistatin, at AA range: 90-170 |
Specificity | Follistatin Polyclonal Antibody detects endogenous levels of Follistatin protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | FST |
Accession No. | P19883 P47931 P21674 |
Alternate Names | FST; Follistatin; FS; Activin-binding protein |
Description | follistatin(FST) Homo sapiens Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | TGF-beta, |
Protein Expression | Pancreas, |
Subcellular Localization | extracellular region, |
Protein Function | function:Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH).,similarity:Contains 1 TB (TGF-beta binding) domain.,similarity:Contains 3 follistatin-like domains.,similarity:Contains 3 Kazal-like domains.,subunit:Monomer .,tissue specificity:Isoform 1 is the predominant isoform in serum but is undetectable in follicular fluid., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |