ITT1738
ITT1738
- Catalog: ITT1738
- Gene/Protein: FOSB
- Product Description: Immunotag™ Fos B Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | FOS B |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,IF,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Monkey |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human FosB. AA range:12-61 |
Specificity | Fos B Polyclonal Antibody detects endogenous levels of Fos B protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | FOSB |
Accession No. | P53539 P13346 |
Alternate Names | FOSB; G0S3; Protein fosB; G0/G1 switch regulatory protein 3 |
Description | FosB proto-oncogene, AP-1 transcription factor subunit(FOSB) Homo sapiens The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
Protein Expression | Blood,Brain, |
Subcellular Localization | nucleus, |
Protein Function | function:FosB interacts with Jun proteins enhancing their DNA binding activity.,similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. Fos subfamily.,similarity:Contains 1 bZIP domain.,subunit:Heterodimer., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |