ITT1750
ITT1750
- Catalog: ITT1750
- Gene/Protein: FOXI1
- Product Description: Immunotag™ FoxI1 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | FOXI1 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | IHC-p,WB,ELISA |
Recommended Dilution | WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human FOXI1. AA range:191-240 |
Specificity | FoxI1 Polyclonal Antibody detects endogenous levels of FoxI1 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | FOXI1 |
Accession No. | Q12951 Q922I5 |
Alternate Names | FOXI1; FKHL10; FREAC6; Forkhead box protein I1; Forkhead-related protein FKHL10; Forkhead-related transcription factor 6; FREAC-6; Hepatocyte nuclear factor 3 forkhead homolog 3; HFH-3; HNF-3/fork-head homolog 3 |
Description | forkhead box I1(FOXI1) Homo sapiens This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it is possible that this gene plays an important role in the development of the cochlea and vestibulum, as well as embryogenesis. Mutations in this gene may be associated with the common cavity phenotype. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
Protein Expression | Colon,Kidney, |
Subcellular Localization | nucleus, |
Protein Function | function:Transcriptional activator required for the development of normal hearing, sense of balance and kidney function. Required for the expression of SLC26A4/PDS, JAG1 and COCH in a subset of epithelial cells and the development of the endolymphatic system in the inner ear. Also required for the expression of SLC4A1/AE1, SLC4A9/AE4, ATP6V1B1 and the differentiation of intercalated cells in the epithelium of distal renal tubules.,similarity:Contains 1 fork-head DNA-binding domain.,tissue specificity:Expressed in kidney., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |