ITT1820
ITT1820
- Catalog: ITT1820
- Gene/Protein: SLC6A11
- Product Description: Immunotag™ GABA T-3 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | GABA T-3 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from GABA T-3, at AA range: 370-450 |
| Specificity | GABA T-3 Polyclonal Antibody detects endogenous levels of GABA T-3 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | SLC6A11 |
| Accession No. | P48066 P31650 P31647 |
| Alternate Names | SLC6A11; GABT3; GAT3; Sodium- and chloride-dependent GABA transporter 3; GAT-3; Solute carrier family 6 member 11 |
| Description | solute carrier family 6 member 11(SLC6A11) Homo sapiens The protein encoded by this gene is a sodium-dependent transporter that uptakes gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, which ends the GABA neurotransmission. Defects in this gene may result in epilepsy, behavioral problems, or intellectual problems. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015], |
| Protein Expression | Brain,Fetal brain, |
| Subcellular Localization | cytoplasm,plasma membrane,integral component of plasma membrane,integral component of membrane,neuron projection, |
| Protein Function | function:Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.,similarity:Belongs to the sodium:neurotransmitter symporter (SNF) family.,tissue specificity:Widespread distribution in the brain., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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