ITT1847
ITT1847
- Catalog: ITT1847
- Gene/Protein: MCM3AP
- Product Description: Immunotag™ GANP Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | GANP |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GANP. AA range:1841-1890 |
| Specificity | GANP Polyclonal Antibody detects endogenous levels of GANP protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | MCM3AP |
| Accession No. | O60318 Q9WUU9 |
| Alternate Names | MCM3AP; GANP; KIAA0572; MAP80; 80 kDa MCM3-associated protein; Protein GANP |
| Description | minichromosome maintenance complex component 3 associated protein(MCM3AP) Homo sapiens The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. This gene is expressed in the brain or in neuronal tissue. An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability. [provided by RefSeq, Jan 2014], |
| Cell Pathway/ Category | Protein_Acetylation |
| Protein Expression | Brain,Skin, |
| Subcellular Localization | nucleus,nuclear pore,nucleoplasm,cytoplasm,cytosol,integral component of membrane,nuclear membrane, |
| Protein Function | function:May be involved in the nuclear localization pathway of MCM3.,similarity:Belongs to the SAC3 family.,subunit:Interacts with MCM3., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
| English_US |
|
| Danish |
|
| Dutch |
|
| English_UK |
|
| French |
|
| German |
|
| Spanish |
|
| Norwegian |
|
| Portuguese |
|
| Finnish |
|
| Swedish |
|
| Polish |
|