ITT1875
ITT1875
- Catalog: ITT1875
- Gene/Protein: KAT2A
- Product Description: Immunotag™ GCN5 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | GCN5 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GCN5L2. AA range:691-740 |
| Specificity | GCN5 Polyclonal Antibody detects endogenous levels of GCN5 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | KAT2A |
| Accession No. | Q92830 Q9JHD2 |
| Alternate Names | KAT2A; GCN5; GCN5L2; HGCN5; Histone acetyltransferase KAT2A; General control of amino acid synthesis protein 5-like 2; Histone acetyltransferase GCN5; HsGCN5; Lysine acetyltransferase 2A; STAF97 |
| Description | lysine acetyltransferase 2A(KAT2A) Homo sapiens KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM, Sep 2009], |
| Cell Pathway/ Category | Protein_Acetylation |
| Subcellular Localization | nuclear chromatin,extracellular space,nucleus,nucleoplasm,Ada2/Gcn5/Ada3 transcription activator complex,STAGA complex,transcription factor TFTC complex,mitotic spindle, |
| Protein Function | somitogenesis, regionalization, chromatin organization, chromatin remodeling, transcription, transcription, DNA-dependent, regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter,transcription from RNA polymerase II promoter, protein amino acid acetylation, pattern specification process,embryonic development ending in birth or egg hatching, anterior/posterior pattern formation, chromatin modification,covalent chromatin modification, histone modification, histone acetylation, histone deubiquitination, protein deubiquitination, RNA biosynthetic process, segmentation, chordate embryonic development, protein amino acid acylation, histone H3 acetylation, regulation of transcription, regulation of RNA metabolic process, chromosome organization, protein modification by small protein removal, protein modification by small protein conjugation or removal, |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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