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ITT1940

ITT1940
  • Catalog: ITT1940
  • Gene/Protein: GNRH1
  • Product Description: Immunotag™ GnRH I Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ GnRH I Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein GnRH I
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application IHC-p,ELISA
Recommended Dilution Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen The antiserum was produced against synthesized peptide derived from human GnRH I. AA range:43-92
Specificity GnRH I Polyclonal Antibody detects endogenous levels of GnRH I protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name GNRH1
Accession No. P01148 P13562
Alternate Names GNRH1; GNRH; GRH; LHRH; Progonadoliberin-1; Progonadoliberin I
Description gonadotropin releasing hormone 1(GNRH1) Homo sapiens This gene encodes a preproprotein that is proteolytically processed to generate a peptide that is a member of the gonadotropin-releasing hormone (GnRH) family of peptides. Alternative splicing results in multiple transcript variants, at least one of which is secreted and then cleaved to generate gonadoliberin-1 and GnRH-associated peptide 1. Gonadoliberin-1 stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutations in this gene are associated with hypogonadotropic hypogonadism. [provided by RefSeq, Nov 2015],
Cell Pathway/ Category GnRH,
Protein Expression Brain,
Subcellular Localization extracellular region,extracellular space,mitochondrion,Golgi-associated vesicle,dendrite,perikaryon,axon terminus,cytoplasmic side of rough endoplasmic reticulum membrane,neurosecretory vesicle,
Protein Function function:Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.,online information:Gonadotropin-releasing hormone entry,pharmaceutical:Available under the names Factrel (Ayerst Labs), Lutrepulse or Lutrelef (Ferring Pharmaceuticals) and Relisorm (Serono). Used in evaluating hypothalamic-pituitary gonadotropic function.,similarity:Belongs to the GnRH family.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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