ITT1940
ITT1940
- Catalog: ITT1940
- Gene/Protein: GNRH1
- Product Description: Immunotag™ GnRH I Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | GnRH I |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | IHC-p,ELISA |
Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human GnRH I. AA range:43-92 |
Specificity | GnRH I Polyclonal Antibody detects endogenous levels of GnRH I protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | GNRH1 |
Accession No. | P01148 P13562 |
Alternate Names | GNRH1; GNRH; GRH; LHRH; Progonadoliberin-1; Progonadoliberin I |
Description | gonadotropin releasing hormone 1(GNRH1) Homo sapiens This gene encodes a preproprotein that is proteolytically processed to generate a peptide that is a member of the gonadotropin-releasing hormone (GnRH) family of peptides. Alternative splicing results in multiple transcript variants, at least one of which is secreted and then cleaved to generate gonadoliberin-1 and GnRH-associated peptide 1. Gonadoliberin-1 stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutations in this gene are associated with hypogonadotropic hypogonadism. [provided by RefSeq, Nov 2015], |
Cell Pathway/ Category | GnRH, |
Protein Expression | Brain, |
Subcellular Localization | extracellular region,extracellular space,mitochondrion,Golgi-associated vesicle,dendrite,perikaryon,axon terminus,cytoplasmic side of rough endoplasmic reticulum membrane,neurosecretory vesicle, |
Protein Function | function:Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.,online information:Gonadotropin-releasing hormone entry,pharmaceutical:Available under the names Factrel (Ayerst Labs), Lutrepulse or Lutrelef (Ferring Pharmaceuticals) and Relisorm (Serono). Used in evaluating hypothalamic-pituitary gonadotropic function.,similarity:Belongs to the GnRH family., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |