ITT2038
ITT2038
- Catalog: ITT2038
- Gene/Protein: GPRC5C
- Product Description: Immunotag™ GPRC5C Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | GPRC5C |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IF,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat,Monkey |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from GPRC5C, at AA range: 30-110 |
Specificity | GPRC5C Polyclonal Antibody detects endogenous levels of GPRC5C protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | GPRC5C |
Accession No. | Q9NQ84 Q8K3J9 Q3KRC4 |
Alternate Names | GPRC5C; RAIG3; PSEC0087; G-protein coupled receptor family C group 5 member C; Retinoic acid-induced gene 3 protein; RAIG-3 |
Description | G protein-coupled receptor class C group 5 member C(GPRC5C) Homo sapiens The protein encoded by this gene is a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The specific function of this protein is unknown; however, this protein may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
Protein Expression | Colon mucosa,Pancreas,Placenta, |
Subcellular Localization | integral component of plasma membrane,integral component of membrane,cytoplasmic vesicle membrane,vesicle,receptor complex,extracellular exosome, |
Protein Function | function:Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways.,induction:By all-trans retinoic acid (ATRA).,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the G-protein coupled receptor 3 family.,subcellular location:Localized in the plasma membrane and perinuclear vesicles.,tissue specificity:Expression is highest in the periphery, particularly in the stomach, but also in the kidney, liver, pancreas, and prostate. In brain, levels of expression are generally lower than in the periphery, with the exception of cerebellum, spinal cord, and dorsal root ganglia (DRG)., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |