ITT2072
ITT2072
- Catalog: ITT2072
- Gene/Protein: GRK7
- Product Description: Immunotag™ GRK 7 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | GRK 7 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IF,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GRK7. AA range:371-420 |
| Specificity | GRK 7 Polyclonal Antibody detects endogenous levels of GRK 7 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | GRK7 |
| Accession No. | Q8WTQ7 |
| Alternate Names | GRK7; GPRK7; G protein-coupled receptor kinase 7; G protein-coupled receptor kinase GRK7 |
| Description | G protein-coupled receptor kinase 7(GRK7) Homo sapiens This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. It is specifically expressed in the retina and the encoded protein has been shown to phosphorylate cone opsins and initiate their deactivation. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Chemokine,Endocytosis, |
| Protein Expression | Retina, |
| Subcellular Localization | photoreceptor disc membrane, |
| Protein Function | catalytic activity:ATP + [G-protein-coupled receptor] = ADP + [G-protein-coupled receptor] phosphate.,function:Phosphorylates cone opsins thereby initiating their deactivation.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 RGS domain.,tissue specificity:Retina. Cones and rod., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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