ITT2092
ITT2092
- Catalog: ITT2092
- Gene/Protein: GNAI3
- Product Description: Immunotag™ Gα i-3 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Gα i-3 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from Gα i-3, at AA range: 1-80 |
| Specificity | Gα i-3 Polyclonal Antibody detects endogenous levels of Gα i-3 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | GNAI3 |
| Accession No. | P08754 Q9DC51 P08753 |
| Alternate Names | GNAI3; Guanine nucleotide-binding protein G(k) subunit alpha; G(i) alpha-3 |
| Description | G protein subunit alpha i3(GNAI3) Homo sapiens Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes an alpha subunit and belongs to the G-alpha family. Mutation in this gene, resulting in a gly40-to-arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway. [provided by RefSeq, Jun 2012], |
| Cell Pathway/ Category | Chemokine,Axon guidance,Tight junction,Gap junction,Leukocyte transendothelial migration,Long-term depression,Progesterone-mediated oocyte maturation,Melanogenesis, |
| Protein Expression | Liver, |
| Subcellular Localization | cytoplasm,lysosomal membrane,Golgi apparatus,centrosome,heterotrimeric G-protein complex,plasma membrane,membrane,midbody,zymogen granule,membrane raft,extracellular exosome, |
| Protein Function | function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(k) is the stimulatory G protein of receptor-regulated K(+) channels.,similarity:Belongs to the G-alpha family. G(i/o/t/z) subfamily.,subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with GPSM1., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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