ITT2096
ITT2096
- Catalog: ITT2096
- Gene/Protein: GNB5
- Product Description: Immunotag™ Gβ 5 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Gβ 5 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from Gβ 5, at AA range: 120-200 |
| Specificity | Gβ 5 Polyclonal Antibody detects endogenous levels of Gβ 5 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | GNB5 |
| Accession No. | O14775 P62881 P62882 |
| Alternate Names | GNB5; Guanine nucleotide-binding protein subunit beta-5; Gbeta5; Transducin beta chain 5 |
| Description | G protein subunit beta 5(GNB5) Homo sapiens Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternatively spliced transcript variants encoding different isoforms exist. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | PI3K/Akt, Insulin Receptor, SAPK_JNK, AMPK |
| Protein Expression | Lymph,Muscle,Uterus, |
| Subcellular Localization | photoreceptor outer segment,photoreceptor inner segment,nucleus,cytosol,plasma membrane,myelin sheath, |
| Protein Function | function:Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.,similarity:Belongs to the WD repeat G protein beta family.,similarity:Contains 7 WD repeats.,subunit:G proteins are composed of 3 units, alpha, beta and gamma. Component of the RGS9-1-Gbeta5 complex composed of RGS9 (isoform RGS9-1), Gbeta5 (GNB5) and RGS9BP.,tissue specificity:Expressed in multiple tissues., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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