ITT2126
ITT2126
- Catalog: ITT2126
- Gene/Protein: LIPC
- Product Description: Immunotag™ Hepatic Lipase Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | Hepatic Lipase |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human LIPC. AA range:301-350 |
| Specificity | Hepatic Lipase Polyclonal Antibody detects endogenous levels of Hepatic Lipase protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | LIPC |
| Accession No. | P11150 P27656 |
| Alternate Names | LIPC; HTGL; Hepatic triacylglycerol lipase; HL; Hepatic lipase; Lipase member C |
| Description | lipase C, hepatic type(LIPC) Homo sapiens LIPC encodes hepatic triglyceride lipase, which is expressed in liver. LIPC has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Glycerolipid metabolism, |
| Protein Expression | Donated clones,Liver,Thymus, |
| Subcellular Localization | extracellular region,extracellular space,endoplasmic reticulum lumen,high-density lipoprotein particle, |
| Protein Function | catalytic activity:Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.,disease:Defects in LIPC are the cause of hepatic lipase deficiency (HL deficiency) [MIM:151670].,function:Hepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL metabolism. Hepatic lipase binds heparin.,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the AB hydrolase superfamily. Lipase family.,similarity:Contains 1 PLAT domain., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
| English_US |
|
| Danish |
|
| Dutch |
|
| English_UK |
|
| French |
|
| German |
|
| Spanish |
|
| Norwegian |
|
| Portuguese |
|
| Finnish |
|
| Swedish |
|
| Polish |
|