ITT2186
ITT2186
- Catalog: ITT2186
- Gene/Protein: HMGN2
- Product Description: Immunotag™ HMG-17 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | HMG-17 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,IF,ELISA |
| Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from HMG-17, at AA range: 10-90 |
| Specificity | HMG-17 Polyclonal Antibody detects endogenous levels of HMG-17 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | HMGN2 |
| Accession No. | P05204 P09602 P18437 |
| Alternate Names | HMGN2; HMG17; Non-histone chromosomal protein HMG-17; High mobility group nucleosome-binding domain-containing protein 2 |
| Description | high mobility group nucleosomal binding domain 2(HMGN2) Homo sapiens The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMGN1, the encoded protein may help maintain an open chromatin configuration around transcribable genes. The protein has also been found to have antimicrobial activity against bacteria, viruses and fungi. [provided by RefSeq, Oct 2014], |
| Protein Expression | Brain,Colon,Eye,Lung,Lymph,Mammary gland,Muscle,Peripheral |
| Subcellular Localization | chromatin,nucleus,cytoplasm, |
| Protein Function | function:Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in an unique chromatin conformation.,mass spectrometry: PubMed:10739259,PTM:Phosphorylation favors cytoplasmic localization.,similarity:Belongs to the HMGN family.,subcellular location:Cytoplasmic enrichment upon phosphorylation., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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