ITT2242
ITT2242
- Catalog: ITT2242
- Gene/Protein: HSPA1L/HSPA1A
- Product Description: Immunotag™ HSP70 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | HSP8000 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from HSP70, at AA range: 190-270 |
| Specificity | HSP70 Polyclonal Antibody detects endogenous levels of HSP70 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | HSPA1L/HSPA1A |
| Accession No. | P34931/P08107 P55063/Q07439 |
| Alternate Names | HSPA1L; Heat shock 70 kDa protein 1-like; Heat shock 70 kDa protein 1L; Heat shock 70 kDa protein 1-Hom; HSP70-Hom; HSPA1A; HSPA1; HSPA1B; Heat shock 70 kDa protein 1A/1B; Heat shock 70 kDa protein 1/2; HSP70-1/HSP70-2; HSP70.1/HSP70.2 |
| Description | heat shock protein family A (Hsp70) member 1 like(HSPA1L) Homo sapiens This gene encodes a 70kDa heat shock protein. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which also encode isoforms of the 70kDa heat shock protein. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Spliceosome,MAPK_ERK_Growth,MAPK_G_Protein,Endocytosis,Antigen processing and presentation, |
| Protein Expression | Stomach mucosa,Testis, |
| Subcellular Localization | zona pellucida receptor complex,nucleoplasm,mitochondrial matrix,cytosol,COP9 signalosome,cell body,blood microparticle, |
| Protein Function | function:In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.,induction:Not induced by heat shock.,similarity:Belongs to the heat shock protein 70 family.,tissue specificity:Expressed in spermatids., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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