ITT2288
ITT2288
- Catalog: ITT2288
- Gene/Protein: IGF1
- Product Description: Immunotag™ IGF-I Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | IGF-I |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from the Internal region of human IGF-I |
| Specificity | IGF-I Polyclonal Antibody detects endogenous levels of IGF-I protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | IGF1 |
| Accession No. | P01343/P05019 P08025 |
| Alternate Names | IBP1; IGF-IA; IGF1A; IGFI; insulin-like growth factor 1; insulin-like growth factor IA; mechano growth factor; MGF; somatomedin C |
| Description | insulin like growth factor 1(IGF1) Homo sapiens The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015], |
| Cell Pathway/ Category | Oocyte meiosis,p53,mTOR,Focal adhesion,Long-term depression,Progesterone-mediated oocyte maturation,Aldosterone-regulated sodium reabsorption,Pathways in cancer,Glioma,Prostate cancer,Melanoma,Hypertrophic cardiomyopathy (HCM),Dilated cardiomyopathy, |
| Protein Expression | Brain,Liver,PCR rescued clones, |
| Subcellular Localization | extracellular region,extracellular space,plasma membrane,insulin-like growth factor binding protein complex,platelet alpha granule lumen,alphav-beta3 integrin-IGF-1-IGF1R complex,insulin-like growth factor ternary complex,exocytic vesicle, |
| Protein Function | disease:Defects in IGF1 are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) [MIM:608747]. IGF1 deficiency is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation.,function:The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity.,online information:Insulin-like growth factor 1 entry,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the insulin family., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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