ITT2318
ITT2318
- Catalog: ITT2318
- Gene/Protein: IL17RA
- Product Description: Immunotag™ IL-17Rα Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | IL-17Rα |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human IL17RA. AA range:141-190 |
| Specificity | IL-17Rα Polyclonal Antibody detects endogenous levels of IL-17Rα protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | IL17RA |
| Accession No. | Q96F46 Q60943 |
| Alternate Names | IL17RA; IL17R; Interleukin-17 receptor A; IL-17 receptor A; IL-17RA; CDw217; CD antigen CD217 |
| Description | interleukin 17 receptor A(IL17RA) Homo sapiens Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014], |
| Cell Pathway/ Category | Cytokine-cytokine receptor interaction, |
| Protein Expression | T-cell,Uterus, |
| Subcellular Localization | extracellular region,plasma membrane,integral component of plasma membrane, |
| Protein Function | function:Receptor for IL17A. Binds its ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling.,PTM:Glycosylated.,tissue specificity:Widely expressed., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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