ITT2353
ITT2353
- Catalog: ITT2353
- Gene/Protein: ITPKB
- Product Description: Immunotag™ InsP 3-kinase B Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | InsP 3-kinase B |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from InsP 3-kinase B, at AA range: 130-210 |
| Specificity | InsP 3-kinase B Polyclonal Antibody detects endogenous levels of InsP 3-kinase B protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | ITPKB |
| Accession No. | P27987 P42335 |
| Alternate Names | ITPKB; Inositol-trisphosphate 3-kinase B; Inositol 1; 4,5-trisphosphate 3-kinase B; IP3 3-kinase B; IP3K B; InsP 3-kinase B |
| Description | inositol-trisphosphate 3-kinase B(ITPKB) Homo sapiens The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Inositol phosphate metabolism,Calcium,Phosphatidylinositol signaling system, |
| Protein Expression | Brain,Cerebellum,Colon,Hippocampus,Platelet,Skin, |
| Subcellular Localization | nucleus,cytosol,membrane, |
| Protein Function | catalytic activity:ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate.,enzyme regulation:IP3K is activated by calmodulin. Form B is much more sensitive to calcium/calmodulin than form A.,similarity:Belongs to the inositol phosphokinase (IPK) family., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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