ITT2355
ITT2355
- Catalog: ITT2355
- Gene/Protein: IPPK
- Product Description: Immunotag™ InsP5 2-kinase Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | InsP5 2-kinase |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,IF,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from InsP5 2-kinase, at AA range: 30-110 |
| Specificity | InsP5 2-kinase Polyclonal Antibody detects endogenous levels of InsP5 2-kinase protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | IPPK |
| Accession No. | Q9H8X2 Q6P1C1 Q5PXE9 |
| Alternate Names | IPPK; C9orf12; Inositol-pentakisphosphate 2-kinase; IPK1 homolog; Inositol-1; 3,4,5,6-pentakisphosphate 2-kinase; Ins(1,3,4,5,6)P5 2-kinase; InsP5 2-kinase |
| Description | inositol-pentakisphosphate 2-kinase(IPPK) Homo sapiens The protein encoded by this gene is a kinase that phosphorylates position 2 of inositol-1,3,4,5,6-pentakisphosphate to form inositol-1,2,3,4,5,6-hexakisphosphate (InsP6). InsP6 has a variety of functions, including stimulation of DNA repair, endocytosis, and mRNA export. [provided by RefSeq, Nov 2010], |
| Cell Pathway/ Category | Inositol phosphate metabolism,Phosphatidylinositol signaling system, |
| Protein Expression | Spinal cord,Teratocarcinoma,Testis, |
| Subcellular Localization | intracellular,nucleus,nucleoplasm,cytosol, |
| Protein Function | catalytic activity:ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + 1D-myo-inositol hexakisphosphate.,domain:The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.,function:Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). InsP6 is involved in many processes such as mRNA export, non-homologous end-joining, endocytosis, ion channel regulation. It also protects cells from TNF-alpha-induced apoptosis.,similarity:Belongs to the IPK1 type 2 family.,tissue specificity:Ubiquitously expressed, with high expression in heart, brain, testis and placenta., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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