ITT2373
ITT2373
- Catalog: ITT2373
- Gene/Protein: ITGB5
- Product Description: Immunotag™ Integrin β5 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | Integrin β5 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat,Monkey |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human Integrin beta5. AA range:721-770 |
Specificity | Integrin β5 Polyclonal Antibody detects endogenous levels of Integrin β5 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | ITGB5 |
Accession No. | P18084 O70309 |
Alternate Names | ITGB5; Integrin beta-5 |
Description | function:Integrin alpha-V/beta-5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.,similarity:Belongs to the integrin beta chain family.,similarity:Contains 1 PSI domain.,similarity:Contains 1 VWFA domain.,subunit:Heterodimer of an alpha and a beta subunit. Beta-5 associates with alpha-V., |
Cell Pathway/ Category | Focal adhesion,ECM-receptor interaction,Regulates Actin and Cytoskeleton,Hypertrophic cardiomyopathy (HCM),Arrhythmogenic right ventricular cardiomyopathy (ARVC),Dilated cardiomyopathy, |
Protein Expression | Brain,Kidney,Thymic epithelium, |
Subcellular Localization | plasma membrane,focal adhesion,integrin complex,cell surface,integrin alphav-beta5 complex,receptor complex,phagocytic vesicle,extracellular exosome, |
Protein Function | function:Integrin alpha-V/beta-5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.,similarity:Belongs to the integrin beta chain family.,similarity:Contains 1 PSI domain.,similarity:Contains 1 VWFA domain.,subunit:Heterodimer of an alpha and a beta subunit. Beta-5 associates with alpha-V., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |