ITT2517
ITT2517
- Catalog: ITT2517
- Gene/Protein: KCNAB3
- Product Description: Immunotag™ KVβ.3 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | KVβ.3 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from KVβ3, at AA range: 270-350 |
| Specificity | KVβ.3 Polyclonal Antibody detects endogenous levels of KVβ.3 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | KCNAB3 |
| Accession No. | O43448 P97382 Q63494 |
| Alternate Names | KCNAB3; KCNA3B; Voltage-gated potassium channel subunit beta-3; K(+) channel subunit beta-3; Kv-beta-3 |
| Description | potassium voltage-gated channel subfamily A regulatory beta subunit 3(KCNAB3) Homo sapiens This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. The encoded protein is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. The encoded protein forms a heterodimer with the potassium voltage-gated channel, shaker-related subfamily, member 5 gene product and regulates the activity of the alpha subunit. [provided by RefSeq, May 2012], |
| Protein Expression | Brain,Epithelium, |
| Subcellular Localization | cytoplasm,plasma membrane,integral component of membrane, |
| Protein Function | domain:Alteration of functional properties of alpha subunit is mediated through N-terminal domain of beta subunit.,function:Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. Alters the functional properties of Kv1.5.,similarity:Belongs to the shaker potassium channel beta subunit family.,subunit:Forms heteromultimeric complex with alpha subunits.,tissue specificity:Brain specific. Most prominent expression in cerebellum. Weaker signals detected in cortex, occipital lobe, frontal lobe and temporal lobe. Not detected in spinal cord, heart, lung, liver, kidney, pancreas, placenta and skeletal muscle., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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