ITT2534
ITT2534
- Catalog: ITT2534
- Gene/Protein: TOR1AIP1
- Product Description: Immunotag™ LAP1B Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | LAP1B |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human TOR1AIP1. AA range:431-480 |
Specificity | LAP1B Polyclonal Antibody detects endogenous levels of LAP1B protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | TOR1AIP1 |
Accession No. | Q5JTV8 Q921T2 |
Alternate Names | TOR1AIP1; Torsin-1A-interacting protein 1; Lamin-associated protein 1B; LAP1B |
Description | torsin 1A interacting protein 1(TOR1AIP1) Homo sapiens This gene encodes a type 2 integral membrane protein that binds A- and B-type lamins. The encoded protein localizes to the inner nuclear membrane and may be involved in maintaining the attachment of the nuclear membrane to the nuclear lamina during cell division. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2016], |
Protein Expression | Cervix,Embryo,Epithelium,Liver,Ovarian carcinoma,Peripheral blood,U |
Subcellular Localization | nucleus,nuclear inner membrane,integral component of membrane, |
Protein Function | function:Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the TOR1AIP family.,subunit:Interacts with TOR1A., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |