ITT2552
ITT2552
- Catalog: ITT2552
- Gene/Protein: LDOC1
- Product Description: Immunotag™ LDOC1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | LDOC1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human LDOC1. AA range:21-70 |
| Specificity | LDOC1 Polyclonal Antibody detects endogenous levels of LDOC1 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | LDOC1 |
| Accession No. | O95751 Q7TPY9 |
| Alternate Names | LDOC1; BCUR1; Protein LDOC1; Leucine zipper protein down-regulated in cancer cells |
| Description | leucine zipper down-regulated in cancer 1(LDOC1) Homo sapiens The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. [provided by RefSeq, Jul 2008], |
| Protein Expression | Brain,Fetal brain, |
| Subcellular Localization | nucleus,nucleolus, |
| Protein Function | function:May have an important role in the development and/or progression of some cancers.,similarity:Belongs to the LDOC1 family.,tissue specificity:Ubiquitously expressed with high levels in brain ant thyroid and low expression in placenta, liver and leukocytes. Expressed as well in six of the seven human breast cancer cell lines examined., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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