ITT2560
ITT2560
- Catalog: ITT2560
- Gene/Protein: CDH17
- Product Description: Immunotag™ LI-cadherin Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | LI-cadherin |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,IF,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CDH17. AA range:341-390 |
| Specificity | LI-cadherin Polyclonal Antibody detects endogenous levels of LI-cadherin protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | CDH17 |
| Accession No. | Q12864 Q9R100 |
| Alternate Names | CDH17; Cadherin-17; Intestinal peptide-associated transporter HPT-1; Liver-intestine cadherin; LI-cadherin |
| Description | cadherin 17(CDH17) Homo sapiens This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009], |
| Cell Pathway/ Category | Adherens_Junction |
| Protein Expression | Colon adenocarcinoma,Epithelium,Trachea, |
| Subcellular Localization | plasma membrane,cell surface,membrane,integral component of membrane,basolateral plasma membrane, |
| Protein Function | function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport.,similarity:Contains 7 cadherin domains.,tissue specificity:Expressed in the gastrointestinal tract and pancreatic duct. Not detected in kidney, lung, liver, brain, adrenal gland and skin., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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