ITT2581
ITT2581
- Catalog: ITT2581
- Gene/Protein: AGPAT3
- Product Description: Immunotag™ LPAAT-γ Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | LPAAT-γ |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human AGPAT3. AA range:121-170 |
Specificity | LPAAT-γ Polyclonal Antibody detects endogenous levels of LPAAT-γ protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | AGPAT3 |
Accession No. | Q9NRZ7 Q9D517 |
Alternate Names | AGPAT3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma; 1-acylglycerol-3-phosphate O-acyltransferase 3; 1-AGP acyltransferase 3; 1-AGPAT 3; Lysophosphatidic acid acyltransferase gamma; LPAAT-gamma |
Description | 1-acylglycerol-3-phosphate O-acyltransferase 3(AGPAT3) Homo sapiens The protein encoded by this gene is an acyltransferase that converts lysophosphatidic acid into phosphatidic acid, which is the second step in the de novo phospholipid biosynthetic pathway. The encoded protein may be an integral membrane protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | Glycerolipid metabolism,Glycerophospholipid metabolism,Ether lipid metabolism, |
Protein Expression | Brain,Fetal liver,Melanoma,Skin,Testis, |
Subcellular Localization | Golgi membrane,nuclear envelope,endoplasmic reticulum,endoplasmic reticulum membrane,plasma membrane,membrane,integral component of membrane, |
Protein Function | catalytic activity:Acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate.,domain:The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.,function:Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.,pathway:Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 2/3.,similarity:Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |