ITT2607
ITT2607
- Catalog: ITT2607
- Gene/Protein: LYL1
- Product Description: Immunotag™ Lyl-1 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | LYL1 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | IHC-p,ELISA |
Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from Lyl-1, at AA range: 120-200 |
Specificity | Lyl-1 Polyclonal Antibody detects endogenous levels of Lyl-1 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | LYL1 |
Accession No. | P12980 P27792 Q66HH3 |
Alternate Names | LYL1; BHLHA18; Protein lyl-1; Class A basic helix-loop-helix protein 18; bHLHa18; Lymphoblastic leukemia-derived sequence 1 |
Description | LYL1, basic helix-loop-helix family member(LYL1) Homo sapiens This gene represents a basic helix-loop-helix transcription factor. The encoded protein may play roles in blood vessel maturation and hematopoeisis. A translocation between this locus and the T cell receptor beta locus (GeneID 6957) on chromosome 7 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Sep 2010], |
Protein Expression | Lymph, |
Subcellular Localization | nucleus, |
Protein Function | disease:A chromosomal aberration involving LYL1 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(7;19)(q35;p13) with TCRB.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |