ITT2613
ITT2613
- Catalog: ITT2613
- Gene/Protein: CHRM4
- Product Description: Immunotag™ mAChR M4 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | mAChR M4 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IF,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from mAChR M4, at AA range: 210-290 |
Specificity | mAChR M4 Polyclonal Antibody detects endogenous levels of mAChR M4 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | CHRM4 |
Accession No. | P08173 P32211 P08485 |
Alternate Names | CHRM4; Muscarinic acetylcholine receptor M4 |
Description | cholinergic receptor muscarinic 4(CHRM4) Homo sapiens The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | Neuroactive ligand-receptor interaction,Regulates Actin and Cytoskeleton, |
Protein Expression | Brain, |
Subcellular Localization | plasma membrane,integral component of plasma membrane,cell junction,synapse,postsynaptic membrane, |
Protein Function | function:The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase.,similarity:Belongs to the G-protein coupled receptor 1 family., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |