ITT2621
ITT2621
- Catalog: ITT2621
- Gene/Protein: MAF1
- Product Description: Immunotag™ Maf1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Maf1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from Maf1, at AA range: 110-190 |
| Specificity | Maf1 Polyclonal Antibody detects endogenous levels of Maf1 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | MAF1 |
| Accession No. | Q9H063 Q9D0U6 Q5XIH0 |
| Alternate Names | MAF1; Repressor of RNA polymerase III transcription MAF1 homolog |
| Description | MAF1 homolog, negative regulator of RNA polymerase III(MAF1) Homo sapiens This gene encodes a protein that is similar to Maf1, a Saccharomyces cerevisiae protein highly conserved in eukaryotic cells. Yeast Maf1 is a negative effector of RNA polymerase III (Pol III). It responds to changes in the cellular environment and represses pol III transcription. Biochemical studies identified the initiation factor TFIIIB as a target for Maf1-dependent repression. [provided by RefSeq, Jul 2008], |
| Protein Expression | Brain,Epithelium,Lung,Uterus, |
| Subcellular Localization | intracellular,nucleus,nucleoplasm,nucleolus,cytoplasm,centrosome,cytosol,plasma membrane,axon,dendrite,intracellular membrane-bounded organelle,perinuclear region of cytoplasm,inhibitor |
| Protein Function | function:Mediator of diverse signals that repress RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.,similarity:Belongs to the MAF1 family.,subunit:Interacts with BRF2., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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