ITT2629
ITT2629
- Catalog: ITT2629
- Gene/Protein: ME1
- Product Description: Immunotag™ Malic enzyme 1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | Malic enzyme 1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from Malic enzyme 1, at AA range: 440-520 |
| Specificity | Malic enzyme 1 Polyclonal Antibody detects endogenous levels of Malic enzyme 1 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | ME1 |
| Accession No. | P48163 P06801 P13697 |
| Alternate Names | ME1; NADP-dependent malic enzyme; NADP-ME; Malic enzyme 1 |
| Description | malic enzyme 1(ME1) Homo sapiens This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Pyruvate metabolism,PPAR, |
| Protein Expression | Liver,Skeletal muscle,Skin,White adipose tissue, |
| Subcellular Localization | mitochondrion,cytosol,plasma membrane, |
| Protein Function | catalytic activity:(S)-malate + NADP(+) = pyruvate + CO(2) + NADPH.,cofactor:Divalent metal cations. Prefers magnesium or manganese.,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the malic enzymes family.,subunit:Homotetramer.,tissue specificity:Expressed in all tissues tested including liver, placenta and white adipose tissue., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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