ITT2636
ITT2636
- Catalog: ITT2636
- Gene/Protein: MAP2
- Product Description: Immunotag™ MAP-2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | MAP-2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from the N-terminal region of human MAP-2 |
| Specificity | MAP-2 Polyclonal Antibody detects endogenous levels of MAP-2 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | MAP2 |
| Accession No. | P11137 P20357 P15146 |
| Alternate Names | MAP2; Microtubule-associated protein 2; MAP-2 |
| Description | microtubule associated protein 2(MAP2) Homo sapiens This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010], |
| Protein Expression | Brain,Brain cortex,Epithelium,Pancreas,Testis, |
| Subcellular Localization | nucleolus,cytoplasm,microtubule,microtubule associated complex,neuron projection, |
| Protein Function | Additional isoforms seem to exist,function:The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.,PTM:MAP2A/c is phosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 3 Tau/MAP repeats.,similarity:Contains 4 Tau/MAP repeats., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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