ITT2657
ITT2657
- Catalog: ITT2657
- Gene/Protein: SERPINB5
- Product Description: Immunotag™ Maspin Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | Maspin |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,IF,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from Maspin, at AA range: 60-140 |
Specificity | Maspin Polyclonal Antibody detects endogenous levels of Maspin protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | SERPINB5 |
Accession No. | P36952 P70124 P70564 |
Alternate Names | SERPINB5; PI5; Serpin B5; Maspin; Peptidase inhibitor 5; PI-5 |
Description | function:Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,tissue specificity:Normal mammary epithelial cells., |
Cell Pathway/ Category | p53, |
Protein Expression | Mammary gland,Oesophagus,Prostate,Small intestine, |
Subcellular Localization | extracellular space,cytoplasm,extracellular exosome, |
Protein Function | function:Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,tissue specificity:Normal mammary epithelial cells., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |