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ITT2682

ITT2682
  • Catalog: ITT2682
  • Gene/Protein: SLC16A12
  • Product Description: Immunotag™ MCT12 Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ MCT12 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein MCT12
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC-p,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human,Mouse
Host Species Rabbit
Immunogen The antiserum was produced against synthesized peptide derived from human MOT12. AA range:115-164
Specificity MCT12 Polyclonal Antibody detects endogenous levels of MCT12 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name SLC16A12
Accession No. Q6ZSM3 Q8BGC3
Alternate Names SLC16A12; MCT12; Monocarboxylate transporter 12; MCT 12; Solute carrier family 16 member 12
Description solute carrier family 16 member 12(SLC16A12) Homo sapiens This gene encodes a transmembrane transporter that likely plays a role in monocarboxylic acid transport. A mutation in this gene has been associated with juvenile cataracts with microcornea and renal glucosuria. [provided by RefSeq, Mar 2010],
Protein Expression Cardiac myocyte,Hippocampus,Skeletal muscle,
Subcellular Localization integral component of plasma membrane,integral component of membrane,
Protein Function disease:Defects in SLC16A12 are a cause of cataract juvenile with microcornea and glucosuria (CJMG) [MIM:612018]. Renal glucosuria is defined by elevated glucose level in the urine without hyperglycemia and without evidence of morphological renal anomalies.,function:Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates.,similarity:Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.,tissue specificity:Most highly expressed in kidney, followed by retina, lung, and testis. Very weakly expressed in brain and liver. Also detected in lens.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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