ITT2682
ITT2682
- Catalog: ITT2682
- Gene/Protein: SLC16A12
- Product Description: Immunotag™ MCT12 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | MCT12 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human MOT12. AA range:115-164 |
Specificity | MCT12 Polyclonal Antibody detects endogenous levels of MCT12 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | SLC16A12 |
Accession No. | Q6ZSM3 Q8BGC3 |
Alternate Names | SLC16A12; MCT12; Monocarboxylate transporter 12; MCT 12; Solute carrier family 16 member 12 |
Description | solute carrier family 16 member 12(SLC16A12) Homo sapiens This gene encodes a transmembrane transporter that likely plays a role in monocarboxylic acid transport. A mutation in this gene has been associated with juvenile cataracts with microcornea and renal glucosuria. [provided by RefSeq, Mar 2010], |
Protein Expression | Cardiac myocyte,Hippocampus,Skeletal muscle, |
Subcellular Localization | integral component of plasma membrane,integral component of membrane, |
Protein Function | disease:Defects in SLC16A12 are a cause of cataract juvenile with microcornea and glucosuria (CJMG) [MIM:612018]. Renal glucosuria is defined by elevated glucose level in the urine without hyperglycemia and without evidence of morphological renal anomalies.,function:Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates.,similarity:Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.,tissue specificity:Most highly expressed in kidney, followed by retina, lung, and testis. Very weakly expressed in brain and liver. Also detected in lens., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |