ITT2701
ITT2701
- Catalog: ITT2701
- Gene/Protein: MEF2B
- Product Description: Immunotag™ MEF-2B Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | MEF-2B |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MEF2B. AA range:51-100 |
| Specificity | MEF-2B Polyclonal Antibody detects endogenous levels of MEF-2B protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | MEF2B |
| Accession No. | Q02080 O55087 |
| Alternate Names | MEF2B; XMEF2; Myocyte-specific enhancer factor 2B; RSRFR2; Serum response factor-like protein 2 |
| Description | BORCS8-MEF2B readthrough(BORCS8-MEF2B) Homo sapiens This gene represents numerous read-through transcripts that span GeneID:729991 and 100271849. Many read-through transcripts are predicted to be nonsense-mediated decay (NMD) candidates, and are thought to be non-coding. Some transcripts are predicted to be capable of translation reinitiation at a downstream AUG, resulting in expression of at least one isoform of myocyte enhancer factor 2B (MEF2B) from this read-through locus. At least one additional MEF2B variant and isoform can be expressed from a downstream promoter, and is annotated on GeneID:100271849. [provided by RefSeq, Oct 2010], |
| Cell Pathway/ Category | AMPK, Protein_Acetylation |
| Protein Expression | Brain,Heart,Placenta,Skeletal muscle, |
| Subcellular Localization | nucleus,transcription factor complex, |
| Protein Function | function:Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Activates transcription via this element. May be involved in muscle-specific and/or growth factor-related transcription.,similarity:Belongs to the MEF2 family.,similarity:Contains 1 MADS-box domain.,similarity:Contains 1 Mef2-type DNA-binding domain.,subunit:Interacts with HDAC7 (By similarity). Heterodimer. Interacts with HDAC9.,tissue specificity:Expressed in skeletal and cardiac muscle and brain., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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