ITT2814
ITT2814
- Catalog: ITT2814
- Gene/Protein: KAT8
- Product Description: Immunotag™ MOF Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | MOF |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | IHC-p,ELISA |
Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from MOF, at AA range: 70-150 |
Specificity | MOF Polyclonal Antibody detects endogenous levels of MOF protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | KAT8 |
Accession No. | Q9H7Z6 Q9D1P2 Q5XI06 |
Alternate Names | KAT8; MOF; MYST1; PP7073; Histone acetyltransferase KAT8; Lysine acetyltransferase 8; MOZ; YBF2/SAS3, SAS2 and TIP60 protein 1; MYST-1; hMOF |
Description | lysine acetyltransferase 8(KAT8) Homo sapiens This gene encodes a member of the MYST histone acetylase protein family. The encoded protein has a characteristic MYST domain containing an acetyl-CoA-binding site, a chromodomain typical of proteins which bind histones, and a C2HC-type zinc finger. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012], |
Protein Expression | Brain,Embryo,Heart,Uterus, |
Subcellular Localization | histone acetyltransferase complex,kinetochore,nucleus,nucleoplasm,MLL1 complex,MSL complex, |
Protein Function | catalytic activity:Acetyl-CoA + histone = CoA + acetylhistone.,function:Histone acetyltransferase which may be involved in transcriptional activation. May influence the function of ATM.,similarity:Belongs to the MYST (SAS/MOZ) family.,similarity:Contains 1 C2HC-type zinc finger.,similarity:Contains 1 chromo domain.,subunit:Component of a multisubunit histone acetyltransferase complex (MSL) at least composed of the MOF/MYST1, MSL1/hampin, MSL2L1 and MSL3L1. Interacts with the chromodomain of MORF4L1/MRG15. Interacts with ATM through the chromodomain., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |