ITT2815
ITT2815
- Catalog: ITT2815
- Gene/Protein: MOK
- Product Description: Immunotag™ MOK Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | MOK |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | IHC-p,ELISA |
Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human MOK. AA range:127-176 |
Specificity | MOK Polyclonal Antibody detects endogenous levels of MOK protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | MOK |
Accession No. | Q9UQ07 Q9WVS4 |
Alternate Names | MOK; RAGE; RAGE1; MAPK/MAK/MRK overlapping kinase; MOK protein kinase; Renal tumor antigen 1; RAGE-1 |
Description | MOK protein kinase(MOK) Homo sapiens This gene belongs to the MAP kinase superfamily. The gene was found to be regulated by caudal type transcription factor 2 (Cdx2) protein. The encoded protein, which is localized to epithelial cells in the intestinal crypt, may play a role in growth arrest and differentiation of cells of upper crypt and lower villus regions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Dec 2012], |
Protein Expression | Brain,Fetal brain,Lung,Renal cell carcinoma,Testis, |
Subcellular Localization | nucleus,cytoplasm,cilium,ciliary base, |
Protein Function | catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Phosphorylation appears to increase the enzymatic activity.,function:Able to phosphorylate several exogenous substrates and to undergo autophosphorylation.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed in heart, brain, lung, kidney, and pancreas, and at very low levels in placenta, liver and skeletal muscle. Detected in retina., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |