ITT2842
ITT2842
- Catalog: ITT2842
- Gene/Protein: ABCC10
- Product Description: Immunotag™ MRP7 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | MRP7 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Monkey |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human MRP7. AA range:835-884 |
Specificity | MRP7 Polyclonal Antibody detects endogenous levels of MRP7 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | ABCC10 |
Accession No. | Q5T3U5 Q8R4P9 |
Alternate Names | ABCC10; MRP7; SIMRP7; Multidrug resistance-associated protein 7; ATP-binding cassette sub-family C member 10 |
Description | ATP binding cassette subfamily C member 10(ABCC10) Homo sapiens The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2010], |
Cell Pathway/ Category | ABC transporters, |
Protein Expression | Small intestine,Spleen,Testis,Uterus, |
Subcellular Localization | lysosomal membrane,plasma membrane,integral component of membrane, |
Protein Function | function:ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion.,similarity:Belongs to the ABC transporter family.,similarity:Belongs to the ABC transporter family. Conjugate transporter (TC 3.A.1.208) subfamily.,similarity:Contains 2 ABC transmembrane type-1 domains.,similarity:Contains 2 ABC transporter domains.,tissue specificity:Isoform 1 is specifically expressed in spleen. Isoform 2 is more widely expressed., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |