ITT2843
ITT2843
- Catalog: ITT2843
- Gene/Protein: MRPL10
- Product Description: Immunotag™ MRP-L10 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | MRPL10 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human MRPL10. AA range:211-260 |
Specificity | MRP-L10 Polyclonal Antibody detects endogenous levels of MRP-L10 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | MRPL10 |
Accession No. | Q7Z7H8 Q3TBW2 |
Alternate Names | MRPL10; MRPL8; RPML8; 39S ribosomal protein L10; mitochondrial; L10mt; MRP-L10; 39S ribosomal protein L8, mitochondrial; L8mt; MRP-L8 |
Description | mitochondrial ribosomal protein L10(MRPL10) Homo sapiens Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode two different isoforms. A pseudogene corresponding to this gene is found on chromosome 5q. [provided by RefSeq, Nov 2010], |
Protein Expression | Pancreas,Skin, |
Subcellular Localization | nucleoplasm,mitochondrion,mitochondrial inner membrane,mitochondrial large ribosomal subunit,ribosome,intracellular ribonucleoprotein complex, |
Protein Function | similarity:Belongs to the ribosomal protein L10P family.,subunit:Component of the mitochondrial ribosome large subunit (39S) which comprises a 16S rRNA and about 50 distinct proteins., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |