ITT2853
ITT2853
- Catalog: ITT2853
- Gene/Protein: MRPL21
- Product Description: Immunotag™ MRP-L21 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | MRPL21 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human MRPL21. AA range:131-180 |
Specificity | MRP-L21 Polyclonal Antibody detects endogenous levels of MRP-L21 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | MRPL21 |
Accession No. | Q7Z2W9 Q9D1N9 |
Alternate Names | MRPL21; 39S ribosomal protein L21; mitochondrial; L21mt; MRP-L21 |
Description | mitochondrial ribosomal protein L21(MRPL21) Homo sapiens Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Multiple transcript variants encoding different isoforms were identified through sequence analysis although some may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Jul 2008], |
Subcellular Localization | mitochondrial inner membrane,mitochondrial large ribosomal subunit,ribosome, |
Protein Function | similarity:Belongs to the ribosomal protein L21P family., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |