ITT2854
ITT2854
- Catalog: ITT2854
- Gene/Protein: MRPL22
- Product Description: Immunotag™ MRP-L22 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | MRPL22 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from MRP-L22, at AA range: 60-140 |
| Specificity | MRP-L22 Polyclonal Antibody detects endogenous levels of MRP-L22 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | MRPL22 |
| Accession No. | Q9NWU5 Q8BU88 P0C2C0 |
| Alternate Names | MRPL22; MRPL25; RPML25; HSPC158; 39S ribosomal protein L22; mitochondrial; L22mt; MRP-L22; 39S ribosomal protein L25, mitochondrial; L25mt; MRP-L25 |
| Description | mitochondrial ribosomal protein L22(MRPL22) Homo sapiens Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for this gene. [provide |
| Protein Expression | Carcinoma,Retina,Skin,Testis,Umbilical cord blood, |
| Subcellular Localization | mitochondrion,mitochondrial inner membrane,mitochondrial large ribosomal subunit,large ribosomal subunit, |
| Protein Function | similarity:Belongs to the ribosomal protein L22P family., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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