ITT2880
ITT2880
- Catalog: ITT2880
- Gene/Protein: MRPS21
- Product Description: Immunotag™ MRP-S21 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | MRPS21 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,IF,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat,Monkey |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human MRPS21. AA range:38-87 |
Specificity | MRP-S21 Polyclonal Antibody detects endogenous levels of MRP-S21 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | MRPS21 |
Accession No. | P82921 P58059 |
Alternate Names | MRPS21; RPMS21; MDS016; 28S ribosomal protein S21; mitochondrial; MRP-S21; S21mt |
Description | mitochondrial ribosomal protein S21(MRPS21) Homo sapiens Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S21P family. Pseudogenes corresponding to this gene are found on chromosomes 1p, 1q, 9p, 10p, 10q, 16q, and 17q. Available sequence data analyses identified splice varian |
Protein Expression | Brain,Cerebellum,Hematopoietic stem cell,Lung,Testis,Uterus, |
Subcellular Localization | mitochondrial inner membrane,mitochondrial small ribosomal subunit,ribosome, |
Protein Function | similarity:Belongs to the ribosomal protein S21P family.,subunit:Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |