ITT2956
ITT2956
- Catalog: ITT2956
- Gene/Protein: PPP1R16A
- Product Description: Immunotag™ MYPT3 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | MYPT3 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human PPP1R16A. AA range:362-411 |
| Specificity | MYPT3 Polyclonal Antibody detects endogenous levels of MYPT3 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | PPP1R16A |
| Accession No. | Q96I34 Q923M0 |
| Alternate Names | PPP1R16A; MYPT3; Protein phosphatase 1 regulatory subunit 16A; Myosin phosphatase-targeting subunit 3 |
| Description | protein phosphatase 1 regulatory subunit 16A(PPP1R16A) Homo sapiens Myosin light chain kinase and phosphatase (MLCP) complexes control the phosphorylation states of regulatory myosin light chains, which is crucial for muscle and intracellular movement. MLCPs typically contain a catalytic protein phosphatase 1 (PP1c) subunit, a myosin phosphatase targeting (MYPT) subunit, and another smaller subunit. The protein encoded by this gene represents an MYPT subunit, which is responsible for directing PP1c to its intended targets. However, while other MYPTs result in PP1c activation after becoming phosphorylated, the encoded protein is phosphorylated by protein kinase A and then inhibits the catalytic activity of PP1c. [provided by RefSeq, Jul 2016], |
| Protein Expression | Lung,Placenta,Spleen,Uterus, |
| Subcellular Localization | plasma membrane, |
| Protein Function | function:Inhibits protein phosphatase 1 activity toward phosphorylase, myosin light chain and myosin substrates.,sequence caution:Cloning artifact.,similarity:Contains 5 ANK repeats.,subunit:Binds PP1., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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