ITT2976
ITT2976
- Catalog: ITT2976
- Gene/Protein: NACAD
- Product Description: Immunotag™ NACAD Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | NACAD |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human NACAD. AA range:376-425 |
| Specificity | NACAD Polyclonal Antibody detects endogenous levels of NACAD protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | NACAD |
| Accession No. | O15069 Q5SWP3 |
| Alternate Names | NACAD; KIAA0363; NAC-alpha domain-containing protein 1 |
| Description | function:May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). May bind to nascent polypeptide chains as they emerge from the ribosome and block their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites).,similarity:Belongs to the NAC-alpha family.,similarity:Contains 1 NAC-A/B (NAC-alpha/beta) domain., |
| Protein Expression | Brain, |
| Subcellular Localization | nucleus,cytoplasm, |
| Protein Function | function:May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). May bind to nascent polypeptide chains as they emerge from the ribosome and block their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites).,similarity:Belongs to the NAC-alpha family.,similarity:Contains 1 NAC-A/B (NAC-alpha/beta) domain., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
| English_US |
|
| Danish |
|
| Dutch |
|
| English_UK |
|
| French |
|
| German |
|
| Spanish |
|
| Norwegian |
|
| Portuguese |
|
| Finnish |
|
| Swedish |
|
| Polish |
|