ITT2988
ITT2988
- Catalog: ITT2988
- Gene/Protein: CDH2
- Product Description: Immunotag™ N-cadherin Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | N-cadherin |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,IF,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from N-cadherin, at AA range: 690-770 |
| Specificity | N-cadherin Polyclonal Antibody detects endogenous levels of N-cadherin protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | CDH2 |
| Accession No. | P19022 P15116 Q9Z1Y3 |
| Alternate Names | CDH2; CDHN; NCAD; Cadherin-2; CDw325; Neural cadherin; N-cadherin; CD antigen CD325 |
| Description | cadherin 2(CDH2) Homo sapiens This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. This protein plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone. [provided by RefSeq, Nov 2015], |
| Cell Pathway/ Category | Cell adhesion molecules (CAMs),Arrhythmogenic right ventricular cardiomyopathy (ARVC), |
| Protein Expression | Brain,Epithelium,Liver, |
| Subcellular Localization | cytoplasm,plasma membrane,cell-cell junction,cell-cell adherens junction,fascia adherens,focal adhesion,intercalated disc,membrane,integral component of membrane,basolateral plasma membrane,apical plasma membrane,catenin complex, |
| Protein Function | function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism.,similarity:Contains 5 cadherin domains.,subunit:Interacts with CDCP1., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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