ITT2994
ITT2994
- Catalog: ITT2994
- Gene/Protein: SLC24A4
- Product Description: Immunotag™ NCKX4 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | NCKX4 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SLC24A4. AA range:328-377 |
| Specificity | NCKX4 Polyclonal Antibody detects endogenous levels of NCKX4 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | SLC24A4 |
| Accession No. | Q8NFF2 Q8CGQ8 |
| Alternate Names | SLC24A4; NCKX4; Sodium/potassium/calcium exchanger 4; Na(+)/K(+)/Ca(2+)-exchange protein 4; Solute carrier family 24 member 4 |
| Description | solute carrier family 24 member 4(SLC24A4) Homo sapiens This gene encodes a member of the potassium-dependent sodium/calcium exchanger protein family. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jul 2010], |
| Protein Expression | Testis, |
| Subcellular Localization | cytoplasm,plasma membrane,integral component of plasma membrane,membrane, |
| Protein Function | caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).,polymorphism:Genetic variations in SLC24A4 are associated with skin/hair/eye pigmentation type 6 (SHEP6) [MIM:210750]. Hair, eye and skin pigmentation are among the most visible examples of human phenotypic variation, with a broad normal range that is subject to substantial geographic stratification. In the case of skin, individuals tend to have lighter pigmentation with increasing distance from the equator. By contrast, the majority of variation in human eye and hair color is found among individuals of European ancestry, with most other human populations fixed for brown eyes and black hair.,similarity:Belongs to the sodium/potassium/calcium exchanger family. SLC24A subfamily.,tissue specificity:Expressed abundantly in all regions of the brain, aorta, lung and thymus. Expressed at lower levels in the stomach and intestine., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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